New Zealand-born winger Joe Tomane has been recalled to the Australia side for Saturday's Rugby Championship Test against South Africa at Newlands.
Winger Adam Ashley-Cooper and hooker Saia Faingaa are both recalled.
Handre Pollard starts at fly-half ahead of Morne Steyn for the South Africans.
And Teboho Mohaje gets a first start at blindside ahead of World Cup winner Schalk Burger following injuries to Willem Alberts and Francois Louw.
Australia beat South Africa 24-23 in Perth at the start of the month.
Australia: Israel Folau, Adam Ashley-Cooper, Tevita Kuridrani, Matt Toomua, Joe Tomane, Bernard Foley, Nick Phipps; James Slipper, Saia Faingaa, Sekope Kepu, Sam Carter, Rob Simmons, Scott Fardy, Michael Hooper (captain), Ben McCalman.
Replacements: James Hanson, Benn Robinson, Ben Alexander, James Horwill, Scott Higginbotham, Nic White, Kurtley Beale, Rob Horne.
South Africa: Willie le Roux, Cornal Hendricks, Jan Serfontein, Jean de Villiers (captain), Bryan Habana, Handre Pollard, Francois Hougaard; Tendai Mtawarira, Adriaan Strauss, Jannie du Plessis, Eben Etzebeth, Victor Matfield, Marcell Coetzee, Teboho Mohoje, Duane Vermeulen.
Replacements: Bismarck du Plessis, Trevor Nyakane, Marcel van der Merwe, Bakkies Botha, Schalk Burger, Cobus Reinach, Pat Lambie, JP Pietersen.