Bath, Northampton, Wasps and Saracens have all been drawn away from home in the European Champions Cup last eight.
It is the first time since 1998 that England has had four clubs reach the quarter-finals of European rugby's top tier competition.
Saracens travel to Racing Metro, Wasps to Toulon, Northampton to Clermont Auvergne and Bath to Leinster.
Wasps and Saints have been drawn at home in the semis should they win their games over the weekend of 4 April.
|Quarter-final draw (to be played 3/4/5 April)|
|Racing Metro v Saracens|
|Toulon v Wasps|
|Clermont Auvergne v Northampton|
|Leinster v Bath|
All four clubs face difficult challenges though. Pool Four winners Bath, who recovered from losing their first two matches, take on three-time European champions Leinster in Dublin.
|Semi-final draw (to be played 17/18/19 April)|
|Toulon/Wasps v Leinster/Bath|
|Clermont Auvergne/Northampton v Racing Metro/Saracens|
Wasps, who had to wait before confirmation of their progress as one of three runners-up, travel to reigning champions Toulon, who won Pool Three with five wins from their six matches.
In the European Challenge Cup, Exeter host Newcastle in an all Premiership tie, Gloucester take on Connacht at Kingsholm, London Irish host Edinburgh and Newport Gwent Dragons face Cardiff Blues in a Welsh derby.