Ulster trio Craig Gilroy, Rory Best and Franco van der Merwe are among seven Ireland-based players in the Pro12 Dream Team for 2014-2015.
Munster players Tommy O'Donnell and CJ Stander are included, as are Connacht pair Robbie Henshaw and Denis Buckley.
Ospreys trio Dan Biggar, Rhys Webb and Alun Wyn Jones are selected along with Scarlets full-back Liam Williams.
Four Scotland-based players feature - Edinburgh's WP Nel plus Glasgow's Tommy Seymour, Peter Horne and Josh Strauss.
Ospreys half-backs Webb and Biggar led the try-scoring and points-scoring tables respectively before the Six Nations started.
After helping Wales finish third, the duo have returned to aid their team's title push, Webb scoring a try as Ospreys beat Glasgow 21-10 on Friday to go top heading into the final round of matches.
They are joined in the line-up by Ospreys captain Jones, one of just three players - along with Biggar and Williams - to retain a place from last season.
Webb's try against Glasgow was his 10th of the Pro12 season, a tally bettered by only Ulster wing Gilroy, who has 11.
Hooker Best and South African second row Van der Merwe complete the Ulster contingent.
Munster, who are third - level on points with Ospreys and Glasgow, provide two thirds of the back row, with Stander on the blind-side and O'Donnell on the other flank.
Glasgow's Seymour is selected on the right wing while Horne is at inside centre and Strauss at number eight.
Strauss' fellow South African Nel is at tight-head while Buckley is rewarded for an impressive campaign at loose-head.
Henshaw, a regular fixture in Ireland's midfield at 21, is at outside centre while Wales international Williams is again at full-back.
Guinness Pro12 Dream Team: Liam Williams (Scarlets), Tommy Seymour (Glasgow Warriors), Robbie Henshaw (Connacht), Peter Horne (Glasgow Warriors), Craig Gilroy (Ulster), Dan Biggar (Ospreys), Rhys Webb (Ospreys), Denis Buckley (Connacht), Rory Best (Ulster), WP Nel (Edinburgh), Alun Wyn Jones (Ospreys), Franco van der Merwe (Ulster), CJ Stander (Munster), Tommy O'Donnell (Munster), Josh Strauss (Glasgow Warriors).