Back row Jackson Wray says Saracens must still believe they can reach the Premiership semi-finals despite losing to play-off rivals Exeter Chiefs.
Sunday's 24-20 defeat at Allianz Park led to Sarries slipping to fifth in the table on points difference.
The north London club can still finish in the top four with victory over relegated London Welsh in their final game of the league season.
"It is in our hands and still down to us to react well to this," Wray said.
"We can't rest up now as it is not over. We need to go to London Welsh and put in a performance that deserves to be in the semi-finals."
Saracens are now level on 63 points with Exeter in the table and, with a points difference of three less than the Chiefs, several scenarios could still put Sarries into the play-offs.
They will qualify if they secure a bonus-point win and Exeter do not pick up five points against Sale, or if they win and either the Chiefs or Leicester, who play leaders Northampton, suffer defeat.
If Exeter win with a bonus-point, a large victory over the Exiles could be enough for Mark McCall's side to finish in the top four on points difference.
Wray is remaining positive about their chances despite the narrow defeat by Exeter.
"It's not often you potentially lose a game like that and get another shot," the 24-year-old told BBC London 94.9.
"We have a big responsibility to regroup, build on what we need to do, and get what we need.
"London Welsh are a difficult one as they obviously have nothing to play for but yet they are a professional team and will give everything to the end."