|Six Nations 2018: England v Wales|
|Venue: Twickenham Date: Saturday, 10 February Kick-off: 16:45 GMT|
|Coverage: Live radio commentary on BBC Radio 5 live, BBC Radio Wales & BBC Radio Cymru. Live text commentary and report on the BBC website and app.|
England scrum-half Ben Youngs will miss the rest of the Six Nations after damaging knee ligaments in Sunday's victory over Italy.
The Leicester player was injured early on in the 46-15 win in Rome and scans revealed a rupture of the medial collateral ligament in his left knee.
The 28-year-old is due for further assessment this week but is expected to be sidelined for four months.
Richard Wigglesworth of Saracens replaces him in the England squad.
The 34-year-old has won 27 England caps but has not played a Test for his country since 2015.
Danny Care is the only other specialist scrum-half in the squad.
Wasps number eight Nathan Hughes has also been included in head coach Eddie Jones' 32-man squad.
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The 26-year-old has not played since December after damaging knee ligaments in a Champions Cup match for Wasps.
But England have included him in the training camp at their Surrey base, and will assess when he is likely to be available to play during the championship.
Exeter Chiefs front-rower Luke Cowan-Dickie has also been included.
England squad in full:
Backs: Mike Brown (Harlequins), Nathan Earle (Saracens), Harry Mallinder (Northampton Saints), Jonny May (Leicester Tigers), Denny Solomona (Sale Sharks), Anthony Watson (Bath Rugby), Danny Care (Harlequins), Owen Farrell (Saracens), George Ford (Leicester Tigers), Jonathan Joseph (Bath Rugby), Jack Nowell (Exeter Chiefs), Ben Te'o (Worcester Warriors), Richard Wigglesworth (Saracens)
Forwards: James Haskell (Wasps)*, Nathan Hughes (Wasps), Nick Isiekwe (Saracens), Maro Itoje (Saracens), George Kruis (Saracens), Courtney Lawes (Northampton Saints), Joe Launchbury (Wasps), Zach Mercer (Bath Rugby), Chris Robshaw (Harlequins), Sam Simmonds (Exeter Chiefs), Sam Underhill (Bath Rugby), Dan Cole (Leicester Tigers), Luke Cowan-Dickie (Exeter Chiefs), Jamie George (Saracens), Dylan Hartley (Northampton Saints), Alec Hepburn (Exeter Chiefs), Joe Marler (Harlequins)*, Mako Vunipola (Saracens), Harry Williams (Exeter Chiefs).
*unavailable for selection due to suspension