Premier 15s leaders Saracens made amends for January's defeat by Exeter Chiefs with a 34-21 comeback victory at StoneX stadium.
Chiefs led 21-10 at half-time but tries from Lotte Clapp, Vicky Fleetwood and May Campbell turned the tide.
Harlequins remain second after a bruising 62-7 win at Bristol.
A host of England internationals - including Jess Breach, Leanne Riley, Amy Cokayne and Abbie Ward - scored in Quins' nine-try victory.
Fourth-placed Wasps closed the gap on Loughborough Lightning with a dominant 36-14 away win.
Gloucester-Hartpury came out on top in a thrilling mid-table match against Worcester, beating the visitors 28-24.
Warriors had a 24-21 lead as the clock went red but Wales flanker Robyn Lock went over from close range to seal a late victory.
At the bottom of the table, Sale beat 10th-placed DMP Durham Sharks 31-3.