Elena Baltacha, James Ward and Anne Keothavong gave British tennis plenty of reasons to cheer by ensuring five Britons progressed to the second round.
Baltacha battled to beat Karin Knapp of Italy 4-6 6-4 6-0, while Keothavong eased past Spain's Laura Pous-Tio 6-3 6-3.
Ward set up a meeting with America's Mardy Fish after a 4-6 6-0 3-6 6-3 6-3 victory over Spain's Pablo Andujar.
They will be joined by Andy Murray who comfortably beat Nikolay Davydenko.
The British number one needed just over one hour and 30 minutes to beat the Russian 6-1 6-1 6-4 to set up a meeting with either Israel's Dudi Sela or Ivo Karlovic of Croatia.
The quartet's victories, along with Heather Waton's opening-day straight-sets win over Iveta Benesova, made it the best showing for British players at Wimbledon since 2006, when seven players progressed to the second round.
Laura Robson missed out, however, although she did give Francesca Schiavone a scare before falling 2-6 6-4 6-4 to the former French Open champion.
Robson was leading by a set as the experienced 24th seed Schiavone had a medical time-out, and the 18-year-old Briton also had break points in the second set.
"I thought I was in control of it, and then just made a few mistakes and let her get back into the match," said the British number four.
"I definitely believed that I could win. I think I was just trying to go for too much because she was getting more balls back and I was just trying to stay the aggressive player in the point, keep the rallies short."
Baltacha, who was informed on Tuesday that she had been awarded a wildcard to represent Britain at London 2012 in the women's singles, admitted it had been an emotional day.
"I didn't know [about the Olympic wildcard] until Judy [Murray] told me at the end," said the 28-year-old, who was hampered by a hip problem during her first-round win.
"If I had have known, I would have been all over the place and crying my eyes out."
The world number 101 will next play defending champion Petra Kvitova and said she was a "very happy girl".
"I will always remember the moment I found out I was going to be an Olympian. You're talking about the elite people in sport in the whole world," she added.
Keothavong, who next plays Sara Errani of Italy: "I made it a little difficult for myself at times but I felt like I settled into the match well, and I never felt I was going to lose - it was just a case of getting the job done.
"I've played against Errani before and she'll be a tough opponent. I'll have to do things better if I'm going to have a shot. Everyone is beatable on any given day."
Ward savoured the best moment of his career to shock Andujar, who is ranked 137 places above him.
"Of course this is the biggest win of my career," Ward said. "Wimbledon is the biggest tournament in the world.
"Grass isn't Andujar's favourite surface, but he's 36 in the world and wins titles on clay for fun."
British wildcard Johanna Konta, 21, could not cause an upset on her Wimbledon debut as she lost to 30th seed Christina McHale in a marathon encounter.
The match had resumed at 7-7 in the third set after bad light had forced them to stop on Monday.
Konta, who switched nationalities from Australia to Britain in May, eventually lost to the American 6-7 (4-7) 6-2 10-8.
The 21-year-old received huge support on Court 17 during her defeat, which spanned two days and lasted three hours and 10 minutes.
"I had good support, it was good to hear them and from what I heard I think they embraced me," Konta said.
"I feel British and I am happy to finally have GBR next to my name. People who are in touch with tennis will have seen my name around for the last few years. I very much hope that I have been accepted now."
There was good news, too, for Jamie Murray in the men's doubles as the Scot and his partner Eric Butorac beat Andre Begemann and Igor Zelenay 7-6 (7-5) 7-6 (7-3) 4-6 7-6 (7-4).
James Baker will resume his first-round tie with Andy Roddick on Wednesday after play was suspended because of rain with the Briton trailing 7-6 (7-1) 4-2.