The rematch between Nathan Cleverly and Tony Bellew will be at the Echo Arena in Liverpool on Saturday, 22 November.
The bout comes three years after Cleverly beat Bellew to retain his WBO light-heavyweight title.
After losing his WBO title to Sergey Kovalev in August 2013, Welshman Cleverly moved up to cruiserweight.
Bellew followed Cleverly into the division after losing to Canada's Adonis Stevenson in a WBC light-heavyweight title fight in 2013.
Cleverly stopped Alejandro Emilio Valori on his cruiserweight debut in July 2014, on the same Liverpool bill that saw Bellew beat Julio Cesar Dos Santos.
A bitter feud between Bellew and Cleverly was reignited following the former's win over Dos Santos.
The winner of the next bout is likely to qualify for a world title fight, possibly against WBO cruiserweight champion Marco Huck from Germany.