Paralympic great Baroness Grey-Thompson says Lord Coe is a future president of the International Olympic Committee (IOC).
Coe has been elected as the president of the IAAF, athletics' governing body.
Grey-Thompson, an 11-time Paralympic gold medallist, welcomed the former Olympic 1500m champion's appointment, but believes it is a "stepping stone".
"I don't think this is the end for him," Grey-Thompson said. "I think he's going to end up as IOC president."
She added: "Probably six years from now you could see him making another move."
Coe, 58, who won gold medals at the 1980 and 1984 Olympics, beat Ukrainian Sergey Bubka, a former Olympic pole vault champion, by 115 votes to 92.
The former chairman of London 2012 and ex-Conservative MP, Coe replaces 82-year-old Senegalese Lamine Diack, who has been in charge for 16 years.
The sport has been hit with a series of doping allegations and Grey-Thompson says Coe must deal with the fall-out.
"He's not taking over at the easiest time, given the revelations over the last few weeks," Grey-Thompson told BBC Radio Wales.
"His manifesto didn't include an awful lot on anti-doping. I think for the public this is something he should tackle very quickly and take a hard line."